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Her family said the 54-year-old had been taken from prison to a local hospital after a sharp deterioration in her health.
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Her family said the 54-year-old had been taken from her prison in north-west Iran to a local hospital, calling the move a "last-minute" action that may come too late.
Mohammadi's brother Hamidreza, who lives in Norway, told the BBC's Newshour programme he fears she is dying, and that he wakes up "waiting for the worst call" he could get.
Narges Mohammadi was awarded the 2023 Nobel Peace Prize. She was arrested in December for her criticism of the authorities.
Last month, Hamidreza Mohammadi said his sister had been found unconscious by fellow inmates at Zanjan Prison in north-west Iran, after suffering a suspected heart attack.
He added that prison officials had refused to transfer her to a hospital despite her history of cardiac, lung and blood pressure problems.
The Narges Mohammadi Foundation, run by her family, said on Friday that she had been transferred to a hospital in Zanjan province "following a catastrophic deterioration in her health".
The statement added that it came "after 140 days of arbitrary detention and the persistent denial of specialised healthcare".
On Saturday, Hamidreza Mohammadi told the BBC his sister was suffering from low blood pressure and had had a heart attack.
He said her previous conditions, including a pulmonary embolism and having undergone stenting and angiography, made "any treatment by the doctors in Zanjan effectively impossible".
He said his sister should be transferred to a hospital in Tehran "so that her own specialists, who have treated her previously, can take over her care".
The call was echoed by Jorgen Watne Frydnes, head of the Nobel Peace Prize committee, who told Reuters news agency that Mohammadi
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